Changed behavior of autofill is a small thing. A few weeks ago, I could enter the first few letters of a site and then down arrow to choose one from the list. Down arrow no longer works here.

A significantly bigger issue allowing a website to open a window or tab or popup. There used to be two buttons when this happens, allow and always allow. Always allow is no longer a choice. I have to click allow every single time I go to that web site. Since two of those sites are the enrollment and learning management systems where I work, I'm doing that 20 times a day. If disappearing the always allow button was a design decision, it was a bad one.