Start Firefox in Safe Mode {web link} by holding down the <Shift> (Mac=Options) key, and then starting Firefox.

A small dialog should appear. Click Start In Safe Mode (not Refresh). Is the problem still there?

https://support.mozilla.org/kb/Firefox+is+already+running+but+is+not+responding

https://support.mozilla.org/en-US/kb/firefox-slow-how-make-it-faster

https://support.mozilla.org/en-US/kb/firefox-uses-too-many-cpu-resources-how-fix

https://support.mozilla.org/en-US/kb/firefox-hangs-or-not-responding

I did it already as I described in the post.

If it works in Safe Mode and in normal mode with all extensions ("3-bar" menu button# or Tools -> Add-ons -> Extensions) disabled then try to find which extension is causing the problem by enabling one extension at a time until the problem reappears.

Close and restart Firefox after each change via one of these:

• "3-bar" menu button# -> Exit (Power button)
• Windows: File -> Exit
• Mac: Firefox -> Quit Firefox
• Linux: File -> Quit

You can try to disable hardware acceleration in Firefox.

• Options/Preferences -> Advanced -> General -> Browsing: "Use hardware acceleration when available"

You need to close and restart Firefox after toggling this setting.

• https://support.mozilla.org/en-US/kb/troubleshoot-extensions-themes-to-fix-problems

You can check if there is an update for your graphics display driver and check for hardware acceleration related issues.

• https://support.mozilla.org/en-US/kb/upgrade-graphics-drivers-use-hardware-acceleration