Is there any way to eliminate annoying popups

I'm not sure there will be a good way to tell apart the annoying ones from the rest, but there will be tools. Are you getting them on some specific site, or from an add–on or search provider, or from some other content?

Any site seems to be affected

I'd personally go check in this order:

Popups: Pop-up blocker settings, exceptions and troubleshooting Notifications: Web Push notifications in Firefox Addons: What to do when searches take you to the wrong search website Malware: Troubleshoot Firefox issues caused by malware