Can a T-Bird 60 profile be used with T-bird 68?

Yes.

Is there a reason for asking this? Are you experiencing an issue ?

Yes, to avoid manually entering account info, address books, and calendars. I used the "thunderbird.exe -p" command to point it to my T-Bird 60 profile backup, which it accepted, but still starts by asking to set up a new account, and none of my email accounts show on the UI.