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Users are regularly getting broken profiles and Thunderbird comes up as a blank window.
-- Win10 Pro 2004 (happened in 1909 also) 64bit -- Using Win10 roaming profiles (but saving actual mail folders on C drive - problem also happens when storing in default location in roaming folder) -- Thunderbird 78.2.1 (and previous) - no addons
Very frequently some users launch Thunderbird and only a blank window appears. The panels exist but there are no folders and account/profile is broken. The options hamburger menu button is there but clicking on it does not generate the menu. Cannot access the troubleshooter window from the help menu either - ie. click Help -> Troubleshooting Information does nothing.
Troubleshooting steps tried, all result with same blank window:
Restart in safe mode, addon disabled Delete files: parent.lock session.json xulstore.json Delete everything in: C:\Users\<WinUsername>\AppData\Local\Thunderbird\Profiles
Only steps that work is to create a new Thunderbird profile and set up all mail accounts again.
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Image of what Thunderbird looks like when profile breaks.