"Your Firefox profile cannot be loaded. It may be missing or inaccessible." CANNOT open profile manager
Using a Mac OS X Version 10.5.8
After some things were changed with server settings, this problem started. I cleared out firefox profiles in the Library. I did try the solutions given elsewhere on this page, but was unable to open the profile manager which seems to be the key. Have removed and reinstalled Firefox several times.
Svi odgovori (1)
If by clearing profiles in the library means you just deleted them that could be a contributor to original problem and the problem with the File Manager not being able to find files. Above the Profiles folder is a Firefox folder and it contains profiles.ini file (and the Profiles folder) which consists of the names and locations of the profiles and and a number for order. This is the reason that it is best to let Firefox create a profile and then you can wipe out the content of the profile and replace it with backed up copy of a profile.
http://kb.mozillazine.org/Profiles.ini_file
Please mark "Solved" one answer that will best help others with a similar problem -- hope this was it.