I simply cannot start Thunderbird despite all my efforts. Thunderbird -p still gives me this error. I had: moved User data to F: from C: to save space on a small SSD and Thunderbird worked great Then: F: (an SSD) crashed, wiping out my User info, resulting in the Profile Missing error. I have: Tried Thunderbird -p in all its configurations including all variants of -p, full file addresses including one to profile stored in old user folder on C: Uninstalled Thunderbird Cleaned the registry renamed all Thunderbird folders to Thunderbirdxxx Downloaded fresh install file Reinstalled Thunderbird to a drive different than previous installation. Torn all my hair out Regardless of what I try, Thunderbird always gives me the Profile Missing error and it refuses to create a new default profile. What might I be missing?