do you select the save option in the dialog asking for the password?

I have the same issue that practically every time I open Thunderbird, it asks for all my e-mail accounts passwords. I've even gone into the system preferences and updated each password, which works for a short time, then the problem returns. It is a real pain - so has anyone found a resolution?

what anti virus are you using?

I get the anti-virus program via my e-mail provider cox.net and they use MacFee.

Restart the operating system in '''[http://en.wikipedia.org/wiki/Safe_mode safe mode with Networking]'''. This loads only the very basics needed to start your computer while enabling an Internet connection. Click on your operating system for instructions on how to start in safe mode: [http://windows.microsoft.com/en-us/windows-8/windows-startup-settings-safe-mode Windows 8], [http://windows.microsoft.com/en-us/windows/start-computer-safe-mode#start-computer-safe-mode=windows-7 Windows 7], [http://windows.microsoft.com/en-us/windows/start-computer-safe-mode#start-computer-safe-mode=windows-vista Windows Vista], [http://www.microsoft.com/resources/documentation/windows/xp/all/proddocs/en-us/boot_failsafe.mspx?mfr=true" Windows XP], [http://support.apple.com/kb/ht1564 OSX] ; If safe mode for the operating system fixes the issue, there's other software in your computer that's causing problems. Possibilities include but not limited to: AV scanning, virus/malware, background downloads such as program updates.