no longer able to retrieve or send emails

Hello there I have had Thunderbird for a number of years on the same Windows 10 laptop. Current version 153.4.0esr (64-bit) updated today/yesterday trying to resolve the issue. I am able to retrieve messages from two accounts one earlier than the other but not to send any message. None of the others either hotmail, live or gmail. I was able to check individually the email inbox directly and all seems correct. I checked the profiles and found only one. Also old Mail folder for pop no longer in use. ImapMail seems to be correct. As I am writing another account has received messages but unable to send any. This seems really weird! No error messages, or warning , just does not want to behave normally