It is quite weird that the intranet page can be loaded successfully if we refresh the page (in the error page). The error is only triggered when the below conditions are met: (1) Re-open the Firefox browser (2) Visit the intranet page for the first time

There is security software like Avast, Kaspersky, BitDefender and ESET that intercept secure connection certificates and send their own. https://support.mozilla.org/en-US/kb/firefox-cant-load-websites-other-browsers-can https://support.mozilla.org/en-US/kb/firefox-and-other-browsers-cant-load-websites https://support.mozilla.org/en-US/kb/secure-connection-failed-error-message https://support.mozilla.org/en-US/kb/connection-untrusted-error-message [https://support.mozilla.org/en-US/kb/websites-dont-load-troubleshoot-and-fix-errors?redirectlocale=en-US&redirectslug=Error+loading+web+sites Websites don't load - troubleshoot and fix error messages] http://kb.mozillazine.org/Error_loading_websites [https://support.mozilla.org/en-US/kb/what-does-your-connection-is-not-secure-mean What do the security warning codes mean] *MOZILLA_PKIX_ERROR_MITM_DETECTED *uses an invalid security certificate SSL_ERROR_BAD_CERT_DOMAIN *configured their website improperly How to troubleshoot the error code "SEC_ERROR_UNKNOWN_ISSUER" on secure websites https://support.mozilla.org/en-US/kb/troubleshoot-SEC_ERROR_UNKNOWN_ISSUER