Suddenly, all my MSF files were empty!
Thunderbird was closed when my laptop crashed and i rebooted it. When I next opened Thunderbird, it turned out that all of my Mail Summary Files (*.MSF) had been replaced with empty files (0 bytes) and the current date/time. As far as I could tell, none of the other files on my hard disk were damaged in any way. While I was able to restore them from backup, I am trying to figure out what caused this to happen in the first place. Any ideas?
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Anti-virus software is a common cause for these kind of problems. These are some generic suggestions to avoid problems with anti-virus software.
Create an exception in your anti-virus software for the Thunderbird profile folder, so that the anti-virus real-time scanner will not scan it. http://kb.mozillazine.org/Profile_folder_-_Thunderbird
Don't let your anti-virus software scan incoming and outgoing messages.
Don't let your anti-virus software scan attachments.
Don't let your anti-virus software intercept your secure connection to the server.
Remove any add-ons your anti-virus software may have installed in Thunderbird.
Keep it working. http://kb.mozillazine.org/Keep_it_working_-_Thunderbird
And last but not least, backup your Thunderbird profile on a regular basis. https://support.mozilla.org/kb/profiles-where-thunderbird-stores-user-data#w_backing-up-a-profile