Drudgereport includes JavaScript code that refreshes the page. You could disable JavaScript for the drudgereport site, that will stop it from refreshing. You can do that by installing the YesScript extension which allows you to block JavaScript on sites that you specify.

Once I've got YesScript installed, how do I activate it? Where do I find it, in Tools?

It adds a button to the status bar, you click on it to enable/disable scripts on the site that is being displayed.

See also http://userscripts.org/scripts/show/13594

You can also use a bookmarklet like this after you have (re)loaded the web page:

javascript:clearInterval(timer);void(autoRefresh=null);

• http://en.wikipedia.org/wiki/Bookmarklet