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Firefox is already running Error

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I have tried all suggestions from the "Firefox is already running..." page but could not fix the problem.

I don't know if this is a problem, but I have several profile folders (see image). The top one is empty, but two folders below that one, are 2 GB or more in size.

Should I delete some or any of them?

I have tried all suggestions from the "Firefox is already running..." page but could not fix the problem. I don't know if this is a problem, but I have several profile folders (see image). The top one is empty, but two folders below that one, are 2 GB or more in size. Should I delete some or any of them?
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