Window upgrade strikes again. I suggest you try and recover your thunderbird profile data from windows.old on your hard disk. But if you have done a complete clean install, your data may wall be history.

See https://support.mozilla.org/en-US/kb/profiles-tb#w_where-is-my-profile-stored

Window updates strike again and again. My Account's labels are in complete disarray with some labels having lost their messages. As GMail.com has retained messages going back about 2 years, I though I'd start afresh in the hope that a newly installed Thunderbird could pick them up. I uninstalled and reinstalled Thunderbird, only to find it didn't delete the Profiles. Deleted them after making a backup and installed Thunderbird again. Now the 'Clean' Thunderbird won't run because it says the profiles are missing. Surely a new install should create new profiles. How can I install, setup anew and run Thunderbird as if I had never seen it before? In the mean time, I've reinstalled Profiles and am running the thing in a muddle as before. Far from satisfactory.

I have the same ISSUE on MAC , i uninstalled thunderbird because no one other then my colleagues were getting my emails ( other will get them if i send from my phone) so with new install i get " your thunderbird profile can't be loaded cause it is missing" now I can't use thunderbird again???????????

Halaezz said

I have the same ISSUE on MAC , i uninstalled thunderbird because no one other then my colleagues were getting my emails ( other will get them if i send from my phone) so with new install i get " your thunderbird profile can't be loaded cause it is missing" now I can't use thunderbird again???????????

No you do not have the same issue on a MAC. I suggest you ask your own question.

Matt said

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No you do not have the same issue on a MAC. I suggest you ask your own question. </blockquote>

ok I did