What site? Did you try Firefox in Safe Mode? https://support.mozilla.org/en-US/kb/diagnose-firefox-issues-using-troubleshoot-mode#search What security software are you running?

There is security software like Avast, Kaspersky, BitDefender and ESET that intercept secure connection certificates and send their own. https://support.mozilla.org/en-US/kb/firefox-cant-load-websites-other-browsers-can https://support.mozilla.org/en-US/kb/firefox-and-other-browsers-cant-load-websites https://support.mozilla.org/en-US/kb/secure-connection-failed-firefox-did-not-connect https://support.mozilla.org/en-US/kb/websites-dont-load-troubleshoot-and-fix-errors [https://support.mozilla.org/en-US/kb/what-does-your-connection-is-not-secure-mean What do the security warning codes mean]