After the latest update, I can no longer set any break point (Right Click, click on line number or keyboard command) on my pages. I tried some other pages in other sites utilizing the script tag but no break points are allowed. My co-worker was able to set break points in 66.0.5 before we updated him to verify the problem. I re-installed the browser. Co-worker says if the file is a .js file, break points can be set but the rendered MVC site page, nothing can be set. Hope this can help