Just for the record, I am running Firefox 32-bit on Windows 8 64-bit, (because I cannot find an official 64 bit Firefox installation), anyways onto the issue. The issue began Yesterday,and I had Firefox for a while beforehand, February 9th 2013, The following functions are affected by the issue *The UI on the upper right hand side of ALL Firefox windows (browser, options,etc.) *Youtube video interface *flash games *The Entire Download interface *possibly other functions that I did not see These functions are not responding to left mouse clicks, some are not responding to right mouse clicks either, this issue happens after I click somewhere other than those functions (ie. Blank space, text, other functions, open a window,etc.), this issue is temporarily resolved when I use ALT +TAB and return to the page,but the issue returns almost immediately after I click again. Because of this I find myself constantly pressing ALT+TAB,just to go about my regular business. This is not the result of any addons, or extensions (as I disabled them all, and the issue persisted). This issue does not affect other windows (ie. the file explorer,steam,games,etc.) I have not tried other browsers yet, but If I cannot resolve this issue permanently I will consider using an other browser for the sake of efficiency.