Errors when downloading files from web sites

I cannot download files from Firefox anymore on my home computer. I click on the download link and it takes me to another page that is blank. I can download just fine w/o any problems from my work computer, download box/window appears just fine. I'm using the same Windows 7, Firefox 8.0 program and same website that gives me the error message from my home computer. Is there a pop-up blocker, cookie or plug-in that I need to turn off/on? How do I enable downloads so I can save to my home computer?