How/when does this come up?

You may have ad/mal-ware. Further information can be found in this article; https://support.mozilla.org/en-US/kb/troubleshoot-firefox-issues-caused-malware?cache=no

Run most or all of the listed free to use malware scanners. Each works differently. If one program misses something, another may pick it up.

You can check the target line in the Firefox desktop shortcut (right-click: Properties) to make sure nothing is appended after the path to the Firefox program.

• https://support.mozilla.org/en-US/kb/wrong-home-page-opens-when-i-start-firefox-how-fix