How do I fix a 'Profile Missing' pop-up box when I try to start up Fire Fox?

Last night I got a strange error while using Firefox it shut it down and said it needed to back up and restart. It said that it saved my profile and shut down. Then it was impossible to restart so I restarted my computer and from then on I got the above pop-up box whenever I try to restart Firefox with the following text in it "Your Firefox profile cannot be loaded. It may be missing or inaccessible." With an Okay button. I have tried uninstalling and reinstalling Firefox and it does no good.

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